Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158097 | 0.73 | MTNR1A (0.48) | TSHRALDH1A1GLAMAPTCRHBP | |
| SCHEMBL409370 | 0.72 | NR3C2 (0.57) | TSHRALDH1A1GLAMAPTCRHBP | |
| SCHEMBL6567347 | 0.72 | NR3C2 (0.57) | TSHRALDH1A1GLAMAPTCRHBP | |
| Hydrochloric Acid SCHEMBL10684893 | 0.71 | MTNR1A (0.47) | TSHRALDH1A1GLAMAPTCRHBP | |
| SCHEMBL7153293 | 0.71 | MTNR1A (0.47) | TSHRALDH1A1GLAMAPTNR3C2 | |
| Ammonia Solution, Strong SCHEMBL4595141 | 0.71 | MTNR1A (0.47) | TSHRALDH1A1GLAMAPTCRHBP | |
| Iodide SCHEMBL31634397 | 0.70 | NR3C2 (0.55) | TSHRALDH1A1GLAMAPTCRHBP | |
| Bromide SCHEMBL6737911 | 0.70 | NR3C2 (0.55) | TSHRALDH1A1GLAMAPTCRHBP | |
| Hydrochloric Acid SCHEMBL27464725 | 0.70 | NR3C2 (0.55) | TSHRALDH1A1GLAMAPTCRHBP | |
| SCHEMBL7149333 | 0.70 | NR3C2 (0.60) | TSHRALDH1A1GLAMAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228095-B1 | PROCESS FOR THE PREPARATION OF OLEFINIC SILANES AND SILOXANES | UNION CARBIDE CORPORATION (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0228095-A2 | Process for the preparation of olefinic silanes and siloxanes | UNION CARBIDE CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4668812-A | Process for the preparation of olefinic silanes and siloxanes | UNION CARBIDE CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |