Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.83 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SFN | P31947 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008072 | 0.91 | MEN1 (1.00) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL7824542 | 0.86 | MEN1 (0.72) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL17434797 | 0.85 | KMT2A (0.68) | MEN1KMT2AALDH1A1NPC1HPGD | |
| SCHEMBL29389982 | 0.85 | KMT2A (0.68) | MEN1KMT2AALDH1A1NPC1HPGD | |
| SCHEMBL12720508 | 0.84 | MEN1 (0.80) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL4002979 | 0.84 | MEN1 (0.79) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL7814839 | 0.83 | MEN1 (0.68) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL4010958 | 0.82 | MEN1 (0.77) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL28833417 | 0.82 | MEN1 (0.77) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL665304 | 0.81 | MEN1 (0.69) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119137112-A | Quinoline cGAS antagonist compounds | 免疫传感器治疗股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2023-11-09 | — | — | US | disclosed |
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2023-11-09 | — | — | US | disclosed |
| CN-116234802-A | Quinoline CGAS antagonist compounds | 免疫传感器治疗股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| EP-0300454-B1 | BENZAMIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND PLANT GROWTH REGULANT | HODOGAYA CHEMICAL CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-4878942-A | AND HERBICIDE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0300454-A2 | Benzamide derivative, process for its production and plant growth regulant | HODOGAYA CHEMICAL CO., LTD. (JP) | 1989-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | MEN1 1514/4885KMT2A 4371/4885MAPT 3235/4885 |
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | CGAS, GLS2, GLS | MEN1 1514/4885KMT2A 4371/4885MAPT 3235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.