Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652507 | 0.79 | AOC3 (0.45) | ALDH1A1TSHRCNR2OPRM1OPRD1 | |
| SCHEMBL4081568 | 0.78 | HTT (0.55) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2268927 | 0.78 | SIGMAR1 (0.44) | ALDH1A1TSHRHTTOPRM1OPRK1 | |
| SCHEMBL9329761 | 0.75 | HTT (0.53) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL19326604 | 0.75 | HTT (0.53) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11795941 | 0.73 | HDAC3 (0.56) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4974601 | 0.73 | HDAC3 (0.61) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2271807 | 0.72 | TAAR1 (0.46) | ALDH1A1TSHRHTTOPRM1OPRK1 | |
| SCHEMBL134524 | 0.72 | TSHR (0.60) | ALDH1A1TSHRCNR2OPRM1OPRD1 | |
| SCHEMBL2240248 | 0.72 | TDP1 (0.50) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228095-B1 | PROCESS FOR THE PREPARATION OF OLEFINIC SILANES AND SILOXANES | UNION CARBIDE CORPORATION (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0184692-B1 | METHOD OF PREPARATION OF O-SILYLATED KETENE ACETALS AND ENOL ETHERS | UNION CARBIDE CORPORATION (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4780554-A | O-silylated ketene acetals and enol ethers and method of preparation | UNION CARBIDE CORPORATION (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0228095-A2 | Process for the preparation of olefinic silanes and siloxanes | UNION CARBIDE CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4668812-A | Process for the preparation of olefinic silanes and siloxanes | UNION CARBIDE CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0184692-A1 | Method of preparation of o-silylated ketene acetals and enol ethers | UNION CARBIDE CORPORATION (US) | 1986-06-18 | — | — | EP | disclosed |