SCHEMBL9621747

SCHEMBL9621747

COc1ccccc1NC(=O)Oc1cc2cc(Br)ccc2cc1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.70
MAPT P10636 5/20 0.70
POLB P06746 4/20 0.70
MEN1 O00255 4/20 0.70
KDM4E B2RXH2 2/20 0.70
MCL1 Q07820 1/20 0.70
NPSR1 Q6W5P4 1/20 0.70
GAA P10253 1/20 0.50
RECQL P46063 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.44
TUBB4A P04350 1/20 0.44
TUBB P07437 1/20 0.44
TUBA3C P0DPH7 1/20 0.44
TUBA1B P68363 1/20 0.44
TUBA4A P68366 1/20 0.44
TUBB4B P68371 1/20 0.44
TUBB3 Q13509 1/20 0.44
TUBB2A Q13885 1/20 0.44
TUBB8 Q3ZCM7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9250804 0.89 KMT2A (0.58) KMT2AMAPTPOLBMEN1KDM4E
SCHEMBL6430894 0.82 MAPT (1.00) KMT2AMAPTPOLBMEN1KDM4E
SCHEMBL9253543 0.78 PPARG (0.65) KMT2AMAPTPOLBMEN1KDM4E
SCHEMBL12368123 0.77 MAPT (0.74) KMT2AMAPTPOLBMEN1KDM4E
SCHEMBL7768952 0.77 MAPT (0.50) KMT2AMAPTPOLBMEN1KDM4E
SCHEMBL9621995 0.76 PPARG (0.69) KMT2AMAPTPOLBMEN1KDM4E
SCHEMBL10437772 0.76 NPC1 (0.58) KMT2AMAPTPOLBKDM4EMCL1
Phosphoric Acid SCHEMBL10432803 0.75 MAPT (0.65) KMT2AMAPTPOLBMEN1KDM4E
SCHEMBL12368140 0.75 MAPT (0.70) KMT2AMAPTPOLBMEN1KDM4E
SCHEMBL9622065 0.75 KMT2A (0.53) KMT2AMAPTPOLBMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0199973-B1 PROCESS FOR THE PRODUCTION ON THE FIBRE OF WATER INSOLUBLE AZO DYES HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-15 EP disclosed
EP-0300390-B1 TRIFLUOROMETHYL-ALKOXY-ANILIN, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE ICE-COLOUR TECHNIQUE HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-29 EP disclosed
EP-0362725-A1 Process for producing water insoluble azo dyes on the fibre according to the ice-colour technique HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-11 EP disclosed
EP-0199973-A2 Process for the production on the fibre of water insoluble azo dyes HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-05 EP disclosed