Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NCEH1 | Q6PIU2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763880 | 0.84 | KMT2A (0.48) | MAPTKDM4EKMT2AMEN1HPGD | |
| SCHEMBL7769003 | 0.83 | KDM4E (0.46) | MAPTKDM4EKMT2AMEN1LMNA | |
| SCHEMBL10437720 | 0.83 | MAPT (0.44) | MAPTKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL13892401 | 0.82 | ALOX15 (0.47) | MAPTKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL7136988 | 0.82 | KDM4E (0.50) | MAPTKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL9621747 | 0.77 | KMT2A (0.70) | MAPTKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL8661668 | 0.75 | MEN1 (0.59) | MAPTKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL23388820 | 0.74 | ALDH1A1 (0.50) | MAPTKDM4EKMT2AMEN1LMNA | |
| SCHEMBL29750502 | 0.74 | ALDH1A1 (0.50) | MAPTKDM4EKMT2AMEN1LMNA | |
| SCHEMBL26667049 | 0.72 | HPGD (0.48) | MAPTKDM4EPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741128-B1 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | HOFFMANN LA ROCHE (CH) | 2001-06-20 | — | — | EP | disclosed |
| EP-0741128-A2 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-06 | — | — | EP | disclosed |