Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621750 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1GAAATML3MBTL1 | |
| SCHEMBL9621469 | 0.83 | PPARD (0.39) | ALDH1A1CES2 | |
| SCHEMBL9621466 | 0.83 | PPARD (0.39) | ALDH1A1CES2 | |
| SCHEMBL9621723 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1GAAATML3MBTL1 | |
| SCHEMBL14234830 | 0.78 | MTNR1A (0.51) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9621480 | 0.77 | MTNR1A (0.60) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL9621479 | 0.77 | MTNR1A (0.60) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL9689196 | 0.77 | TAAR1 (0.50) | KDM4EL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL9689194 | 0.77 | TAAR1 (0.50) | KDM4EL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL16220582 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1GAAATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323915-B1 | BETA-HYDROXYKETONE AND ITS PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-5101076-A | β-hydroxyketone and its production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-31 | — | — | US | disclosed |
| US-5041679-A | Beta-hydroxyketone and its production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0323915-A1 | Beta-hydroxyketone and its production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-07-12 | — | — | EP | disclosed |