Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR68 | Q15743 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.35 |
| ▸ | TPH1 | P17752 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10773378 | 0.90 | PIM1 (0.43) | GPR68NPSR1HTR1AADORA2AHTR2B | |
| SCHEMBL7754258 | 0.80 | NPSR1 (0.57) | GPR68NPSR1HTR1AADORA2AHTR2B | |
| SCHEMBL6723521 | 0.69 | KCNH3 (0.54) | GPR68NPSR1APP | |
| SCHEMBL14869452 | 0.67 | NPSR1 (0.59) | GPR68NPSR1HTR1AADORA2AHTR2B | |
| SCHEMBL11292840 | 0.66 | MAPT (0.50) | ADORA2ANOS1 | |
| SCHEMBL659100 | 0.65 | TAAR1 (0.70) | HTR1ANOS1NOS2TAAR1DRD2 | |
| SCHEMBL6727019 | 0.65 | NPSR1 (0.74) | GPR68NPSR1HTR1AADORA2AHTR2B | |
| SCHEMBL3301514 | 0.65 | NPSR1 (0.74) | GPR68NPSR1HTR1AADORA2AHTR2B | |
| SCHEMBL14869748 | 0.64 | ACKR3 (0.53) | HTR2BAPPNOS1TAAR1 | |
| Hydrochloric Acid SCHEMBL3957562 | 0.63 | TAAR1 (0.67) | HTR1ANOS1NOS2TAAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240867-B1 | PROCESS FOR THE PREPARATION OF AMINOALKYL- OR -ARYLMELAMINES | BASF Aktiengesellschaft (DE) | 1992-02-19 | — | — | EP | disclosed |