Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | CPA3 | P15088 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436477 | 1.00 | EPHX2 (0.53) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL7436470 | 1.00 | EPHX2 (0.53) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL9622141 | 0.87 | CYP1A2 (0.61) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL7436656 | 0.87 | CYP1A2 (0.61) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL7436651 | 0.87 | CYP1A2 (0.61) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL10521821 | 0.87 | MMP8 (0.61) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL8345051 | 0.86 | HSD17B10 (0.56) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL14874554 | 0.86 | HSD17B10 (0.56) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL13262220 | 0.84 | EPHX2 (0.56) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL15479082 | 0.83 | PPARG (0.58) | EPHX2PPARGMMP8MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166212-A | Hypotensive agents, analgesics | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5021430-A | Enkephalinase inhibitors, analgesics, hypotensives | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| EP-0225292-A2 | Certain N-substituted butyramide derivatives | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | disclosed |