Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775479 | 0.86 | ALDH1A1 (0.39) | ALDH1A1CES2CES1TSHRFFAR3 | |
| SCHEMBL9622068 | 0.81 | HCAR2 (0.35) | HCAR2ALDH1A1LMNA | |
| SCHEMBL9622075 | 0.81 | HCAR2 (0.35) | HCAR2ALDH1A1LMNA | |
| SCHEMBL27261275 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNACES2CES1TSHR | |
| SCHEMBL7697795 | 0.74 | ALDH1A1 (0.33) | ALDH1A1LMNACES2CES1TSHR | |
| SCHEMBL10478960 | 0.74 | TSHR (0.42) | ALDH1A1CES2CES1TSHRFFAR3 | |
| SCHEMBL10478959 | 0.74 | TSHR (0.42) | ALDH1A1CES2CES1TSHRFFAR3 | |
| SCHEMBL1050435 | 0.73 | — | — | |
| SCHEMBL446279 | 0.73 | — | — | |
| SCHEMBL15482493 | 0.72 | HCAR2 (0.48) | HCAR2ALDH1A1LMNAATMCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159098-A | Alk-1-enyloxy carbamates | ISP INVESTMENTS INC. (US) | 1992-10-27 | — | — | US | disclosed |