Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.70 |
| ▸ | CASP1 | P29466 | 3/20 | 0.70 |
| ▸ | CASP7 | P55210 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.69 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.65 |
| ▸ | TUBB | P07437 | 1/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660678 | 0.90 | MKNK2 (0.84) | MEN1KMT2AMAPTKDM4ECYP3A4 | |
| SCHEMBL28040768 | 0.86 | MAPT (0.63) | MEN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL27735205 | 0.84 | MAPT (0.73) | MEN1KMT2AMAPTKDM4ECYP3A4 | |
| SCHEMBL18099391 | 0.84 | MAPT (1.00) | MEN1KMT2AMAPTPOLBCYP3A4 | |
| SCHEMBL29561672 | 0.84 | MKNK2 (0.86) | MEN1KMT2AMAPTPOLBMKNK2 | |
| SCHEMBL30256517 | 0.82 | MEN1 (0.86) | MEN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL3135319 | 0.82 | KDM4E (1.00) | MEN1KMT2AMAPTKDM4ECYP3A4 | |
| SCHEMBL29575749 | 0.82 | MEN1 (0.86) | MEN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL3211188 | 0.82 | MEN1 (0.86) | MEN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL31412250 | 0.82 | KDM4E (1.00) | MEN1KMT2AMAPTKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128429-A | Low temperature block polymerization without randomization | RAYCHEM LIMITED (GB) | 1992-07-07 | — | — | US | disclosed |
| EP-0154506-B1 | PREPARATION OF ORGANIC POLYMERS | RAYCHEM LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| US-4999411-A | Polythioethers, polythiocarbonates, polythioamides, polythioimides | RAYCHEM LIMITED (GB) | 1991-03-12 | — | — | US | disclosed |
| US-4960835-A | ENGINEERING THERMOPLASTICS | RAYCHEM LIMITED (GB) | 1990-10-02 | — | — | US | disclosed |
| US-4845179-A | CONDENSATION POLYMERIZATION | RAYCHEM LIMITED (GB) | 1989-07-04 | — | — | US | disclosed |
| EP-0154506-A2 | Preparation of organic polymers | RAYCHEM LIMITED (GB) | 1985-09-11 | — | — | EP | disclosed |