Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
| ▸ | CPA3 | P15088 | 3/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622311 | 1.00 | TMEM97 (0.47) | TMEM97SIGMAR1CYP1A2SLC1A3SLC1A2 | |
| SCHEMBL9622307 | 1.00 | TMEM97 (0.47) | TMEM97SIGMAR1CYP1A2SLC1A3SLC1A2 | |
| SCHEMBL9259915 | 0.81 | TMEM97 (0.41) | TMEM97SIGMAR1CYP1A2FOLH1CPA3 | |
| SCHEMBL9259921 | 0.81 | TMEM97 (0.41) | TMEM97SIGMAR1CYP1A2FOLH1CPA3 | |
| SCHEMBL839242 | 0.77 | CAPN1 (0.43) | TMEM97SIGMAR1 | |
| SCHEMBL392513 | 0.77 | CAPN1 (0.43) | TMEM97SIGMAR1 | |
| SCHEMBL16241096 | 0.77 | CAPN1 (0.43) | TMEM97SIGMAR1 | |
| SCHEMBL27559601 | 0.77 | TMEM97 (0.46) | TMEM97SIGMAR1CA2 | |
| SCHEMBL6933031 | 0.75 | ALDH1A1 (0.52) | TMEM97SIGMAR1CYP1A2CA2 | |
| SCHEMBL2493185 | 0.75 | ALDH1A1 (0.52) | TMEM97SIGMAR1CYP1A2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166212-A | Hypotensive agents, analgesics | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5021430-A | Enkephalinase inhibitors, analgesics, hypotensives | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| EP-0225292-A2 | Certain N-substituted butyramide derivatives | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | disclosed |