Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.74 |
| ▸ | G6PD | P11413 | 5/20 | 0.67 |
| ▸ | SHBG | P04278 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.67 |
| ▸ | DPP4 | P27487 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | CYP17A1 | P05093 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | GUSB | P08236 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622335 | 1.00 | ALDH1A1 (0.74) | ALDH1A1NR3C1MAPK1SMN1; SMN2SIGMAR1 | |
| SCHEMBL6336489 | 0.90 | ALDH1A1 (0.76) | ALDH1A1NR3C1MAPK1SMN1; SMN2SIGMAR1 | |
| SCHEMBL21594801 | 0.90 | ALDH1A1 (0.76) | ALDH1A1NR3C1MAPK1SMN1; SMN2SIGMAR1 | |
| SCHEMBL7990951 | 0.90 | ALDH1A1 (0.76) | ALDH1A1NR3C1MAPK1SMN1; SMN2SIGMAR1 | |
| SCHEMBL15173566 | 0.90 | ALDH1A1 (0.76) | ALDH1A1NR3C1MAPK1SMN1; SMN2SIGMAR1 | |
| SCHEMBL6336492 | 0.90 | ALDH1A1 (0.76) | ALDH1A1NR3C1MAPK1SMN1; SMN2SIGMAR1 | |
| SCHEMBL3995420 | 0.89 | ALDH1A1 (0.74) | ALDH1A1NR3C1MAPK1SMN1; SMN2SIGMAR1 | |
| SCHEMBL3995417 | 0.89 | ALDH1A1 (0.74) | ALDH1A1NR3C1MAPK1SMN1; SMN2SIGMAR1 | |
| SCHEMBL7990902 | 0.89 | ALDH1A1 (0.74) | ALDH1A1NR3C1MAPK1SMN1; SMN2SIGMAR1 | |
| SCHEMBL6331607 | 0.89 | ALDH1A1 (0.74) | ALDH1A1NR3C1MAPK1SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175154-A | Antiobesity, antidiabetic, antilipemic, anticholesterol agents | RESEARCH CORPORATION TECHNOLOGIES, INC. | 1992-12-29 | — | — | US | disclosed |
| US-4898694-A | 17-Hydroxy-steroids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1990-02-06 | — | — | US | disclosed |