Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2627053 | 0.88 | LCK (0.56) | SIRT1SRD5A2LCKEPHX2NR1H4 | |
| SCHEMBL5712086 | 0.85 | SRD5A2 (0.73) | SIRT1SRD5A2NPC1RAB9AEPHX2 | |
| SCHEMBL284242 | 0.80 | EPHX2 (0.66) | SIRT1SRD5A2NPC1RAB9AEPHX2 | |
| SCHEMBL10946728 | 0.80 | SRD5A2 (0.83) | SIRT1SRD5A2NPC1RAB9AEPHX2 | |
| SCHEMBL1148445 | 0.80 | SRD5A2 (0.83) | SIRT1SRD5A2NPC1RAB9AEPHX2 | |
| Hydrochloric Acid SCHEMBL5012511 | 0.78 | EPHX2 (0.64) | SIRT1SRD5A2NPC1RAB9AEPHX2 | |
| SCHEMBL12451655 | 0.78 | SRD5A2 (0.73) | SIRT1SRD5A2NPC1RAB9AEPHX2 | |
| SCHEMBL12551369 | 0.78 | SRD5A2 (0.73) | SIRT1SRD5A2NPC1RAB9AEPHX2 | |
| Hydrochloric Acid SCHEMBL27713186 | 0.78 | SRD5A2 (0.79) | SIRT1SRD5A2NPC1RAB9AEPHX2 | |
| SCHEMBL2363489 | 0.78 | LCK (0.78) | LCKSMN1; SMN2ALDH1A1KMT2APLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | claimed |
| US-5093516-A | AROMATIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 1992-03-03 | — | — | US | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |