SCHEMBL9622778

SCHEMBL9622778

C=C(C)c1cc2ccccc2s1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.58
HDAC3 O15379 1/20 0.55
HDAC4 P56524 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC7 Q8WUI4 1/20 0.55
HDAC2 Q92769 1/20 0.55
HDAC10 Q969S8 1/20 0.55
HDAC11 Q96DB2 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
HDAC9 Q9UKV0 1/20 0.55
HDAC5 Q9UQL6 1/20 0.55
TUBB4A P04350 1/20 0.53
TUBB P07437 1/20 0.53
TUBA3C P0DPH7 1/20 0.53
TUBA1B P68363 1/20 0.53
TUBA4A P68366 1/20 0.53
TUBB4B P68371 1/20 0.53
TUBB3 Q13509 1/20 0.53
TUBB2A Q13885 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1535950 0.83 BCL2L1 (0.62) BCL2L1HDAC3HDAC4HDAC1HDAC7
SCHEMBL8243714 0.82 BCL2L1 (0.66) BCL2L1HDAC3HDAC4HDAC1HDAC7
SCHEMBL407602 0.80 BCL2L1 (0.69) BCL2L1HDAC3HDAC4HDAC1HDAC7
SCHEMBL12820023 0.80 BCL2L1 (0.58) BCL2L1HDAC3HDAC4HDAC1HDAC7
SCHEMBL24555320 0.77 BCL2L1 (0.55) BCL2L1HDAC3HDAC4HDAC1HDAC7
SCHEMBL18339791 0.77 BCL2L1 (0.59) BCL2L1HDAC3HDAC4HDAC1HDAC7
SCHEMBL22590860 0.77 HDAC1 (0.60) BCL2L1HDAC3HDAC4HDAC1HDAC7
SCHEMBL9233094 0.77 BCL2L1 (0.55) BCL2L1HDAC3HDAC4HDAC1HDAC7
SCHEMBL9233096 0.77 BCL2L1 (0.55) BCL2L1HDAC3HDAC4HDAC1HDAC7
SCHEMBL1444814 0.77 BCL2L1 (0.55) BCL2L1HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10330673-B2 Fluorescent chemical sensor for biological amines THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2019-06-25 US disclosed
WO-2018018863-A1 MILD AND EFFICIENT PREPARATION METHOD FOR Α-ACYLOXY ALKENYL AMIDE COMPOUND AND USE THEREOF IN SYNTHESIS OF AMIDE AND POLYPEPTIDE 江西师范大学 2018-02-01 WO disclosed
US-5166204-A ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME TOYAMA CHEMICAL CO., LTD. (JP) 1992-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10330673-B2 Fluorescent chemical sensor for biological amines ADRB3, SLC18A1, AOC3 BCL2L1 3785/4885HDAC3 340/4885HDAC4 648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.