SCHEMBL9622847

SCHEMBL9622847

CCCCC(C)CS(=O)(=O)CC(C)CCCC

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.40
ACE2 Q9BYF1 1/20 0.38
SLC15A1 P46059 1/20 0.35
DNM1 Q05193 2/20 0.35
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
FDPS P14324 1/20 0.34
CA2 P00918 6/20 0.33
OPRM1 P35372 1/20 0.33
MAPK1 P28482 1/20 0.33
CA1 P00915 4/20 0.32
CA12 O43570 1/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27268372 0.91 ACE2 (0.48) TP53ACE2FDPSCA2OPRM1
SCHEMBL11350925 0.84 TSHR (0.43) TP53TSHRSMN1; SMN2CA2CA1
SCHEMBL8813015 0.83 TP53 (0.39) TP53ACE2SLC15A1DNM1TSHR
SCHEMBL2531832 0.83 TP53 (0.39) TP53ACE2SLC15A1DNM1TSHR
SCHEMBL23181465 0.81 TP53 (0.38) TP53ACE2DNM1TSHRSMN1; SMN2
SCHEMBL5572371 0.81 TP53 (0.47) TP53ACE2SLC15A1FDPSCA2
SCHEMBL27951226 0.81 TP53 (0.42) TP53ACE2CA2OPRM1CA1
SCHEMBL5572373 0.81 TP53 (0.47) TP53ACE2SLC15A1FDPSCA2
SCHEMBL8812271 0.76 TP53 (0.47) TP53ACE2FDPSCA2OPRM1
SCHEMBL2236544 0.76 TP53 (0.47) TP53ACE2FDPSCA2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1221516-C Process for the carbonylation of a conjugated diene DSM NV (NL) 2005-10-05 CN disclosed
US-5110902-A High molecular weight polythioether-sulfones PHILLIPS PETROLEUM COMPANY (US) 1992-05-05 US disclosed
US-5086163-A High molecular weight polymers formed by contacting dihaloaromatic sulfone with complex of alkali metal aminoalkanoate and alkalimetal hydrosulfide PHILLIPS PETROLEUM COMPANY (US) 1992-02-04 US disclosed
US-5015725-A Heat resistant thermoplastic resins for electrical components, aircraft or automobile parts, protective coatings PHILLIPS PETROLEUM COMPANY (US) 1991-05-14 US disclosed
EP-0309955-A1 Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1989-04-05 EP disclosed
US-4125525-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-11-14 US disclosed