Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531832 | 0.93 | TP53 (0.39) | TP53ACE2OPRM1CA1FDPS | |
| SCHEMBL2233250 | 0.83 | TSHR (0.42) | TP53CA1CA2 | |
| SCHEMBL17319467 | 0.83 | TSHR (0.42) | TP53CA1CA2 | |
| SCHEMBL27268372 | 0.82 | ACE2 (0.48) | TP53ACE2OPRM1CA1ADH1B | |
| SCHEMBL8812271 | 0.82 | TP53 (0.47) | TP53ACE2OPRM1CA1ADH1B | |
| SCHEMBL14929193 | 0.81 | OPRM1 (0.44) | TP53ACE2OPRM1CA1ADH1B | |
| SCHEMBL8812277 | 0.80 | TP53 (0.55) | TP53ACE2OPRM1CA1FDPS | |
| SCHEMBL30605502 | 0.80 | TP53 (0.50) | TP53ACE2OPRM1CA1CA2 | |
| SCHEMBL24920097 | 0.78 | ACE2 (0.50) | TP53ACE2OPRM1ADH1BADH1C | |
| SCHEMBL8908063 | 0.78 | TP53 (0.53) | TP53ACE2CA1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360143-B1 | SULFONE COMPOUNDS FOR USE AS SOLVENT FOR ELECTROCHEMICAL DEVICES | SUMITOMO SEIKA CHEMICALS (JP) | 2017-08-16 | — | — | EP | disclosed |
| US-8466324-B2 | Sulfone compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8426208-B2 | Method and apparatus for determining radiation | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120295360-A1 | METHOD AND APPARATUS FOR DETERMINING RADIATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120174324-A1 | DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2012-07-12 | — | — | US | disclosed |
| US-8187887-B2 | Method and apparatus for determining radiation | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-05-29 | — | — | US | disclosed |
| US-20110257438-A1 | SULFONE COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2011-10-20 | — | — | US | disclosed |
| EP-2360143-A1 | SULFONE COMPOUND | Sumitomo Seika Chemicals CO. LTD. (JP) | 2011-08-24 | — | — | EP | disclosed |
| US-20110081724-A1 | METHOD AND APPARATUS FOR DETERMINING RADIATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257438-A1 | SULFONE COMPOUND | SULT1E1, SULT1A1, STS | TP53 4133/4885ACE2 755/4885OPRM1 2225/4885 |
| US-20120174324-A1 | DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE | IK, H1-0, H1-5 | TP53 707/4885ACE2 4346/4885OPRM1 1782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.