Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CDC25B | P30305 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17774946 | 0.85 | IKBKB (0.49) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL21230658 | 0.82 | KDM4E (0.59) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL709947 | 0.82 | HSD17B10 (0.47) | KDM4EKMT2AALDH1A1CDC25BMAPT | |
| SCHEMBL258439 | 0.81 | MYC (0.56) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL31597491 | 0.81 | MYC (0.56) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL23517113 | 0.81 | KDM4E (0.53) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL2030008 | 0.81 | MYC (0.56) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL10625157 | 0.81 | KMT2A (0.57) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL17774904 | 0.80 | MAP4K1 (0.45) | KDM4EALDH1A1MAPTALOX15GAA | |
| SCHEMBL17118247 | 0.80 | F3 (0.44) | KDM4EALDH1A1MAPTTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362244-A1 | PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. | 2017-12-21 | — | — | US | disclosed |
| US-8486938-B2 | Pyrazolo[1,5-a]pyrimidines for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2013-07-16 | — | — | US | disclosed |
| EP-0280187-B1 | HAIR DYEING COMPOSITIONS WITH DIRECT-DYEING NITRO-DIPHENYL AMINE DERIVATIVES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0280187-A1 | Hair dyeing compositions with direct-dyeing nitro-diphenyl amine derivatives | Henkel Kommanditgesellschaft auf Aktien (DE) | 1988-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362244-A1 | PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT | TYMP, ZC3HAV1, TYMS | KDM4E 2069/4885KMT2A 3648/4885GFER 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.