SCHEMBL258439

SCHEMBL258439

CC(=O)Nc1ccc(N)c(C(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.56
KDM4E B2RXH2 4/20 0.55
KMT2A Q03164 2/20 0.53
GFER P55789 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
TDP1 Q9NUW8 2/20 0.52
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
POLB P06746 1/20 0.52
MAPT P10636 1/20 0.52
THRB P10828 1/20 0.52
PKM P14618 1/20 0.52
APEX1 P27695 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
MCL1 Q07820 1/20 0.52
ALDH1A1 P00352 3/20 0.51
GLA P06280 2/20 0.50
KEAP1 Q14145 1/20 0.50
HSD17B10 Q99714 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2030008 1.00 MYC (0.56) MYCKDM4EKMT2AGFERRXFP1
SCHEMBL31597491 1.00 MYC (0.56) MYCKDM4EKMT2AGFERRXFP1
SCHEMBL11097889 0.88 MYC (0.47) MYCKDM4EKMT2AGFERRXFP1
SCHEMBL8980390 0.87 ALDH1A1 (0.53) MYCKDM4EKMT2ATDP1MEN1
SCHEMBL973116 0.86 TDP1 (0.54) MYCKDM4EKMT2ATDP1MEN1
SCHEMBL10625157 0.85 KMT2A (0.57) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL10580566 0.84 KMT2A (0.55) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL2500845 0.83 MYC (0.61) MYCKDM4EKMT2ATDP1MEN1
SCHEMBL7458280 0.83 SMN1; SMN2 (0.64) KDM4EKMT2ATDP1MEN1MAPT
SCHEMBL7453002 0.83 HDAC1 (0.51) KDM4ETDP1ALDH1A1GLAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343556-A Bio-based compound modified cracking carbon black and application thereof in tire preparation 中策橡胶集团股份有限公司 2024-01-05 CN claimed
CN-117247608-A Tire pad rubber composition containing bio-based modified cracking carbon black, mixing method and tire 中策橡胶集团股份有限公司 2023-12-19 CN claimed
CN-117247639-A Tire inner liner rubber composition containing bio-based modified cracking carbon black, mixing method and tire 中策橡胶集团股份有限公司 2023-12-19 CN claimed
CN-114057917-A Post-treatment ashless dispersant and preparation method thereof 中国石油天然气股份有限公司 2022-02-18 CN claimed
CN-111925494-B High-viscosity waterborne polyurethane and preparation method thereof 温州大学新材料与产业技术研究院 2021-12-14 CN claimed
CN-111925494-A High-viscosity waterborne polyurethane and preparation method thereof 温州大学新材料与产业技术研究院 2020-11-13 CN claimed
CN-107602809-B High-solid-content aqueous polyurethane dispersion liquid based on aminocarboxylate and sulfamate simultaneously 温州大学 2020-05-22 CN claimed
CN-107602809-A High-solid content water-based polyurethane dispersion liquid a kind of while based on aminocarboxylate and sulfamate 温州大学 2018-01-19 CN claimed
EP-2109465-A2 POLAR HYDROPHILIC PRODRUGS OF AMPHETAMINE AND OTHER STIMULANTS AND PROCESSES FOR MAKING AND USING THE SAME Kempharm, Inc. (US) 2009-10-21 EP claimed
US-20090239949-A1 Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same SHIRE LLC 2009-09-24 US claimed
WO-2008098151-A2 POLAR HYDROPHILIC PRODRUGS OF AMPHETAMINE AND OTHER STIMULANTS AND PROCESSES FOR MAKING AND USING THE SAME KEMPHARM, INC. (US) 2008-08-14 WO claimed
JP-9279051-A None JP disclosed
US-12599578-B2 Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof Ensysce Biosciences Inc. (US) 2026-04-14 US disclosed
US-20250361205-A1 ENZYME-CLEAVABLE METHADONE PRODRUGS AND METHODS OF USE THEREOF ENSYSCE BIOSCIENCES INC (US) 2025-11-27 US disclosed
US-12384744-B2 Enzyme-cleavable methadone prodrugs and methods of use thereof Ensysce Biosciences Inc. (US) 2025-08-12 US disclosed
US-3989692-A PHTHALOCYANINE DYES, WOOL, SILK, POLYAMIDES, CELLULOSE BAYER AKTIENGESELLSCHAFT (DT) 1976-11-02 US disclosed
US-3988310-A FIBER-REACTIVE DYES; CELLULOSE BAYER AKTIENGESELLSCHAFT (DT) 1976-10-26 US disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239949-A1 Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same SLC6A2, SLC6A3, SLC18A2 MYC 1691/4885KDM4E 2162/4885KMT2A 1364/4885
US-12599578-B2 Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof OPRK1, OPRL1, OPRM1 MYC 4491/4885KDM4E 1350/4885KMT2A 1764/4885
US-12384744-B2 Enzyme-cleavable methadone prodrugs and methods of use thereof CES2, ACHE, COMT MYC 3802/4885KDM4E 1056/4885KMT2A 1230/4885
US-20250361205-A1 ENZYME-CLEAVABLE METHADONE PRODRUGS AND METHODS OF USE THEREOF CES2, ACHE, COMT MYC 3802/4885KDM4E 1056/4885KMT2A 1230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.