SCHEMBL9622907

SCHEMBL9622907

O=C(O)c1cc(Cl)c(OC(CCCOc2c(Cl)cccc2Cl)C(=O)O)c(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 3/20 0.51
FOLH1 Q04609 1/20 0.47
KMT2A Q03164 4/20 0.42
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
MEN1 O00255 3/20 0.40
PPARA Q07869 4/20 0.40
PPARG P37231 4/20 0.40
PTGES O14684 1/20 0.38
ALOX5 P09917 1/20 0.38
PLA2G2A P14555 1/20 0.38
NR4A2 P43354 1/20 0.37
MITF O75030 1/20 0.37
TP53 P04637 1/20 0.37
HPGD P15428 1/20 0.37
XBP1 P17861 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9623483 0.88 MEN1 (0.46) PLAUFOLH1KMT2ANPC1RAB9A
SCHEMBL9623215 0.84 KMT2A (0.40) PLAUFOLH1KMT2ARAB9AMEN1
SCHEMBL9623912 0.80 FOLH1 (0.47) PLAUFOLH1PPARAPPARGPTGES
SCHEMBL9623654 0.78 FOLH1 (0.47) PLAUFOLH1KMT2ANPC1RAB9A
SCHEMBL9623612 0.78 FOLH1 (0.47) PLAUFOLH1PPARAPPARGPTGES
SCHEMBL9623622 0.75 FOLH1 (0.44) FOLH1KMT2APPARAPPARGPTGES
SCHEMBL9623931 0.75 MEN1 (0.48) FOLH1KMT2ANPC1RAB9AMEN1
SCHEMBL9623323 0.74 PLAU (0.79) PLAUKMT2ANPC1RAB9AMEN1
SCHEMBL9623565 0.73 TP53 (0.43) KMT2ANPC1RAB9AMEN1PPARA
SCHEMBL21854479 0.73 PLAU (0.72) PLAUKMT2ANPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed