SCHEMBL9623323

SCHEMBL9623323

O=C(O)c1cc(Cl)c(OCCOc2c(Cl)cc(C(=O)O)cc2Cl)c(Cl)c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.79
TPMT P51580 2/20 0.55
TTR P02766 2/20 0.54
POLB P06746 1/20 0.50
ALOX15 P16050 1/20 0.50
HTT P42858 1/20 0.50
TSHR P16473 1/20 0.47
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
ALDH1A1 P00352 2/20 0.42
GAA P10253 2/20 0.42
ABL1 P00519 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
RIN1 Q13671 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
THRA P10827 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21854479 0.90 PLAU (0.72) PLAUTPMTTTRPOLBALOX15
SCHEMBL566358 0.89 PLAU (0.70) PLAUTPMTTTRPOLBALOX15
SCHEMBL5591733 0.89 PLAU (1.00) PLAUTPMTTTRPOLBALOX15
SCHEMBL11036037 0.88 PLAU (0.64) PLAUALOX15HTTTSHRALDH1A1
SCHEMBL1708361 0.87 PLAU (0.68) PLAUTPMTPOLBALOX15HTT
SCHEMBL9622885 0.87 PLAU (0.62) PLAUPOLBHTTTSHRKMT2A
SCHEMBL9623570 0.87 PLAU (0.62) PLAUTPMTTTRPOLBALOX15
SCHEMBL12432454 0.84 PLA2G2A (0.64) PLAUTSHRTHRATHRB
SCHEMBL6557422 0.84 PLA2G2A (0.64) PLAUTSHRTHRATHRB
SCHEMBL11576418 0.84 PLAU (0.64) PLAUTPMTTTRPOLBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed
US-4587071-A STRETCHING TORAY INDUSTRIES, INC. (JP) 1986-05-06 US disclosed
US-4546030-A SUBJECTING FILM TO MULTISTAGE LONGITUDINAL, TRANSVERSE, AND BIAXIAL STRETCHING TORAY INDUSTRIES, INC. (JP) 1985-10-08 US disclosed
US-4497865-A HIGH TENSILE STRENGTH MAGNETIC TAPES; SHRINKAGE INHIBITION TORAY INDUSTRIES, INC. (JP) 1985-02-05 US disclosed
EP-0086302-A1 Polyethylene terephthalate film, process for the production thereof and magnetic recording medium therefrom TORAY INDUSTRIES, INC. (JP) 1983-08-24 EP disclosed