Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.49 |
| ▸ | NQO2 | P16083 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622459 | 0.87 | PDGFRB (0.47) | KDM4EALDH1A1PDGFRBROCK2MEN1 | |
| SCHEMBL9623031 | 0.84 | PDGFRB (0.50) | KDM4EALDH1A1HPGDPDGFRBROCK2 | |
| Hydrochloric Acid SCHEMBL9623220 | 0.84 | PDGFRB (0.49) | KDM4EALDH1A1HPGDPDGFRBROCK2 | |
| SCHEMBL29386554 | 0.83 | PDGFRB (0.48) | KDM4EALDH1A1PDGFRBROCK2MEN1 | |
| SCHEMBL9622903 | 0.81 | PDGFRB (0.45) | KDM4EALDH1A1HPGDHSD17B10PDGFRB | |
| SCHEMBL9622522 | 0.80 | PDGFRB (0.46) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9622629 | 0.80 | PDGFRB (0.46) | KDM4EALDH1A1HSD17B10PDGFRBROCK2 | |
| Hydrochloric Acid SCHEMBL9623250 | 0.80 | PDGFRB (0.45) | KDM4EALDH1A1HPGDHSD17B10PDGFRB | |
| Bromide SCHEMBL9623160 | 0.79 | PDGFRB (0.44) | KDM4EALDH1A1PDGFRBROCK2MEN1 | |
| SCHEMBL9622974 | 0.77 | ROCK2 (0.44) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |