Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.43 |
| ▸ | HMGCR | P04035 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623128 | 0.95 | CYP4F2 (0.45) | CYP4F2CYP4A11PTPN7HMGCRMEN1 | |
| SCHEMBL1265697 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11MEN1KMT2AKDM4E | |
| SCHEMBL13259428 | 0.79 | MEN1 (0.47) | CYP4F2CYP4A11PTPN7HMGCRMEN1 | |
| SCHEMBL20597662 | 0.79 | CYP4F2 (0.69) | CYP4F2CYP4A11PTPN7HMGCRMEN1 | |
| SCHEMBL6893301 | 0.77 | CYP4F2 (0.46) | CYP4F2CYP4A11MEN1KMT2AKDM4E | |
| SCHEMBL8497297 | 0.76 | ATM (0.65) | PTPN7HMGCRMEN1KMT2ARECQL | |
| SCHEMBL2737131 | 0.74 | CYP4F2 (0.72) | CYP4F2CYP4A11MEN1KMT2AMAPT | |
| SCHEMBL13259358 | 0.73 | MEN1 (0.41) | CYP4F2CYP4A11PTPN7HMGCRMEN1 | |
| SCHEMBL2720899 | 0.73 | CYP4F2 (0.76) | CYP4F2CYP4A11MEN1KMT2AMAPT | |
| SCHEMBL8249184 | 0.73 | CYP4F2 (0.76) | CYP4F2CYP4A11MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274064-B1 | 2,5,6,7-TETRANOR-18,18,19,19-TETRADEHYDRO-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4880939-A | ANTISECRETORY AGENTS, HYPOTENSIVES, ANTICOAGULANTS | TORAY INDUSTRIES (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4775692-A | ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT | TORAY INDUSTRIES, INC. (JP) | 1988-10-04 | — | — | US | disclosed |
| EP-0274064-A2 | 2,5,6,7-Tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1988-07-13 | — | — | EP | disclosed |