Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15551008 | 0.84 | MMP8 (0.43) | CYP4F2CYP4A11MEN1KMT2APKM | |
| SCHEMBL1265697 | 0.84 | CYP4F2 (0.46) | CYP4F2CYP4A11MEN1KMT2APKM | |
| SCHEMBL13259166 | 0.82 | MEN1 (0.48) | CYP4F2CYP4A11MEN1KMT2APKM | |
| SCHEMBL16841345 | 0.81 | MEN1 (0.37) | CYP4F2CYP4A11MEN1KMT2APKM | |
| SCHEMBL2276386 | 0.79 | CYP4F2 (0.42) | CYP4F2CYP4A11MEN1KMT2APKM | |
| SCHEMBL1313228 | 0.79 | CYP4F2 (0.42) | CYP4F2CYP4A11MEN1KMT2APKM | |
| SCHEMBL11449724 | 0.79 | DGAT1 (0.35) | — | |
| SCHEMBL17284530 | 0.78 | MEN1 (0.38) | CYP4F2CYP4A11MEN1KMT2APKM | |
| SCHEMBL9623128 | 0.78 | CYP4F2 (0.45) | CYP4F2CYP4A11MEN1KMT2APKM | |
| SCHEMBL1313060 | 0.78 | CYP4F2 (0.47) | CYP4F2CYP4A11MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637449-B2 | Processes for preparing protease inhibitors of hepatitis C virus | MERCK SHARP & DOHME CORP. (US) | 2014-01-28 | — | — | US | disclosed |
| US-8637449-B2 | Processes for preparing protease inhibitors of hepatitis C virus | MERCK SHARP & DOHME CORP. (US) | 2014-01-28 | — | — | US | disclosed |
| US-20120232247-A1 | PROCESSES FOR PREPARING PROTEASE INHIBITORS OF HEPATITIS C VIRUS | MERCK SHARP & DOHME CORP. | 2012-09-13 | — | — | US | disclosed |
| WO-2011025849-A1 | PROCESSES FOR PREPARING PROTEASE INHIBITORS OF HEPATITIS C VIRUS | MERCK SHARP & DOHME CORP. (US) | 2011-03-03 | — | — | WO | disclosed |
| EP-0274064-B1 | 2,5,6,7-TETRANOR-18,18,19,19-TETRADEHYDRO-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4880939-A | ANTISECRETORY AGENTS, HYPOTENSIVES, ANTICOAGULANTS | TORAY INDUSTRIES (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4775692-A | ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT | TORAY INDUSTRIES, INC. (JP) | 1988-10-04 | — | — | US | disclosed |
| EP-0274064-A2 | 2,5,6,7-Tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1988-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232247-A1 | PROCESSES FOR PREPARING PROTEASE INHIBITORS OF HEPATITIS C VIRUS | RNASE1, TMPRSS15, HAVCR2 | CYP4F2 139/4885CYP4A11 79/4885MEN1 3113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.