Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | IL1RN | P18510 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957128 | 1.00 | POLB (0.44) | POLBGFERGPR84CYP3A4TSHR | |
| SCHEMBL957127 | 1.00 | POLB (0.44) | POLBGFERGPR84CYP3A4TSHR | |
| SCHEMBL963889 | 0.93 | POLB (0.39) | POLBGFERGPR84CYP3A4TSHR | |
| SCHEMBL963890 | 0.93 | POLB (0.39) | POLBGFERGPR84CYP3A4TSHR | |
| SCHEMBL935155 | 0.90 | POLB (0.42) | POLBGFERGPR84CYP3A4TSHR | |
| SCHEMBL936803 | 0.89 | POLB (0.41) | POLBGFERGPR84MAPTALDH1A1 | |
| SCHEMBL935885 | 0.89 | MAPT (0.41) | POLBGFERGPR84ADRB3MAPT | |
| SCHEMBL937949 | 0.88 | POLB (0.41) | POLBGFERGPR84CYP3A4TSHR | |
| SCHEMBL936364 | 0.88 | POLB (0.46) | POLBGFERGPR84CYP3A4TSHR | |
| SCHEMBL936885 | 0.87 | POLB (0.39) | POLBGFERGPR84MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010748-A1 | INDOLE DERIVATIVE AND SALTINESS-STRENGTHENING AGENT CONTAINING THE DERIVATIVE | 味の素株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |