Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL937949 | 0.91 | POLB (0.41) | POLBGFERGAAGPR84STAT3 | |
| SCHEMBL962320 | 0.90 | POLB (0.44) | POLBGFERGPR84STAT3HSD17B10 | |
| SCHEMBL957127 | 0.90 | POLB (0.44) | POLBGFERGPR84STAT3HSD17B10 | |
| SCHEMBL957128 | 0.90 | POLB (0.44) | POLBGFERGPR84STAT3HSD17B10 | |
| SCHEMBL936364 | 0.86 | POLB (0.46) | POLBGFERGAAGPR84STAT3 | |
| SCHEMBL936221 | 0.84 | POLB (0.45) | POLBGFERGAAGPR84STAT3 | |
| SCHEMBL936872 | 0.83 | LMNA (0.45) | POLBGFERGAAGPR84STAT3 | |
| SCHEMBL963889 | 0.83 | POLB (0.39) | POLBGFERGPR84STAT3HSD17B10 | |
| SCHEMBL963890 | 0.83 | POLB (0.39) | POLBGFERGPR84STAT3HSD17B10 | |
| SCHEMBL935586 | 0.82 | POLB (0.51) | POLBGAAGPR84CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010748-A1 | INDOLE DERIVATIVE AND SALTINESS-STRENGTHENING AGENT CONTAINING THE DERIVATIVE | 味の素株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |