Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10598392 | 0.91 | MEN1 (0.43) | MEN1KMT2ATDP1MMP1MMP2 | |
| SCHEMBL17898446 | 0.87 | TDP1 (0.52) | MEN1KMT2ATDP1MMP1MMP2 | |
| SCHEMBL438038 | 0.87 | MEN1 (0.40) | MEN1KMT2ATDP1MMP1MMP2 | |
| SCHEMBL9789513 | 0.85 | MEN1 (0.36) | MEN1KMT2ATDP1 | |
| SCHEMBL27545260 | 0.84 | MEN1 (0.39) | MEN1KMT2ATDP1MMP1MMP2 | |
| SCHEMBL3253082 | 0.83 | MEN1 (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL11283462 | 0.81 | MEN1 (0.40) | MEN1KMT2ATDP1 | |
| SCHEMBL439670 | 0.81 | MEN1 (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL10585220 | 0.81 | MEN1 (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL19688386 | 0.81 | MEN1 (0.47) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302612-B1 | INSECTICIDAL COMPOUNDS CHARACTERISED BY ENHANCED KNOCKDOWN EFFECT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-04 | — | — | EP | claimed |
| US-4927852-A | TETRAFLUOROBENZENE CYCLOPROPANECARBOXYLATES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-22 | — | — | US | claimed |
| EP-0302612-A1 | Insecticidal compounds characterised by enhanced knockdown effect | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-08 | — | — | EP | claimed |
| EP-0302612-B1 | INSECTICIDAL COMPOUNDS CHARACTERISED BY ENHANCED KNOCKDOWN EFFECT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-04 | — | — | EP | disclosed |
| US-4927852-A | TETRAFLUOROBENZENE CYCLOPROPANECARBOXYLATES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-22 | — | — | US | disclosed |
| EP-0302612-A1 | Insecticidal compounds characterised by enhanced knockdown effect | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-08 | — | — | EP | disclosed |