SCHEMBL438038

SCHEMBL438038

COCc1c(F)c(F)c(COC(=O)C2C(C)(C)C2(C)C)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP12 P39900 1/20 0.31
MTOR P42345 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28781650 0.93 MEN1 (0.37) MEN1KMT2ATDP1MTORRAB9A
SCHEMBL28944536 0.93 MEN1 (0.42) MEN1KMT2ATDP1MTORRAB9A
SCHEMBL10598392 0.91 MEN1 (0.43) MEN1KMT2ATDP1MMP1MMP2
SCHEMBL19478311 0.91 MEN1 (0.39) MEN1KMT2ATDP1
SCHEMBL9766139 0.91 MEN1 (0.36) MEN1KMT2ATDP1
SCHEMBL19478257 0.91 MEN1 (0.36) MEN1KMT2ATDP1
SCHEMBL28781639 0.91 MEN1 (0.35) MEN1KMT2ATDP1MTORRAB9A
SCHEMBL28781651 0.91 MEN1 (0.40) MEN1KMT2ATDP1MTORRAB9A
SCHEMBL28781597 0.90 MEN1 (0.34) MEN1KMT2ATDP1
SCHEMBL28781587 0.90 MEN1 (0.37) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240057602-A1 DIAMIDE INSECTICIDE COMPOSITIONS FMC IP TECHNOLOGY GMBH (CH) 2024-02-22 US claimed
US-20230026036-A1 DIAMIDE SUSPENSION CONCENTRATE COMPOSITIONS FMC IP TECHNOLOGY GMBH (CH) 2023-01-26 US claimed
EP-3887354-B1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORP (US) 2023-01-04 EP claimed
US-20220394974-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES FMC CORPORATION 2022-12-15 US claimed
CN-114828628-A Diamide suspension concentrate compositions FMC公司 2022-07-29 CN claimed
EP-4013223-A1 MATERIAL DELIVERY SYSTEMS AND METHODS FMC Corporation (US) 2022-06-22 EP claimed
EP-3996508-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES FMC Corporation (US) 2022-05-18 EP claimed
US-20210400977-A1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORPORATION 2021-12-30 US claimed
EP-3887354-A1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC Corporation (US) 2021-10-06 EP claimed
WO-2021067678-A1 DIAMIDE INSECTICIDE COMPOSITIONS FMC CORPORATION (US) 2021-04-08 WO claimed
WO-2020112390-A1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORPORATION (US) 2020-06-04 WO claimed
US-20150237863-A1 LIQUID INSECTICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-08-27 US claimed
EP-2910121-A1 LIQUID INSECTICIDAL COMPOSITION Sumitomo Chemical Company, Limited (JP) 2015-08-26 EP claimed
US-20140205548-A1 AEROSOL FOR CONTROLLING INDOOR INSECT PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-24 US claimed
US-7459168-B2 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2008-12-02 US claimed
EP-1352562-B1 Insecticide transpiration apparatus DAINIPPON JOCHUGIKU KK (JP) 2006-11-15 EP claimed
US-20060052444-A1 Arthropod controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED 2006-03-09 US claimed
US-20040180070-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2004-09-16 US claimed
EP-1352562-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2003-10-15 EP claimed
US-20030160062-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2003-08-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040180070-A1 Insecticide transpiration apparatus TIMM13, PIK3C3, ATP5PD MEN1 4117/4885KMT2A 3655/4885TDP1 2733/4885
US-20030160062-A1 Insecticide transpiration apparatus PIK3C3, ACHE, ATP5PD MEN1 4401/4885KMT2A 4329/4885TDP1 1190/4885
US-20060052444-A1 Arthropod controlling agent RRP12, NOP2, YTHDF1 MEN1 1035/4885KMT2A 35/4885TDP1 3372/4885
US-20210400977-A1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS DDT, RDX, ACHE MEN1 486/4885KMT2A 752/4885TDP1 460/4885
US-20140205548-A1 AEROSOL FOR CONTROLLING INDOOR INSECT PEST PTMA, PIR, DHCR24 MEN1 1019/4885KMT2A 1859/4885TDP1 3754/4885
US-20240057602-A1 DIAMIDE INSECTICIDE COMPOSITIONS DDT, PLCG2, PLD2 MEN1 3579/4885KMT2A 2162/4885TDP1 539/4885
US-20150237863-A1 LIQUID INSECTICIDAL COMPOSITION SRMS, CTRL, CSTB MEN1 4196/4885KMT2A 325/4885TDP1 2780/4885
US-20220394974-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES ACHE, DDT, BCHE MEN1 2727/4885KMT2A 4453/4885TDP1 1558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.