Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 5/20 | 0.40 |
| ▸ | GLB1 | P16278 | 3/20 | 0.40 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22764802 | 0.95 | CNR2 (0.39) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL20829025 | 0.91 | GBA1 (0.47) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL670536 | 0.89 | GLB1 (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL7115175 | 0.89 | GLB1 (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL18853802 | 0.89 | GLB1 (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL19754907 | 0.89 | ALDH1A1 (0.52) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL12670425 | 0.89 | ALDH1A1 (0.52) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL13253549 | 0.89 | ALDH1A1 (0.52) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL19320446 | 0.89 | ALDH1A1 (0.52) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL12670451 | 0.89 | ALDH1A1 (0.52) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319576-B1 | PROSTAGLANDIN DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) | 1992-01-08 | — | — | EP | disclosed |
| EP-0319576-A1 | PROSTAGLANDIN DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES. | ISTITUTO BIOCHIMICO ITALIANO (IT) | 1989-06-14 | — | — | EP | disclosed |
| WO-1988010252-A1 | PROSTAGLANDIN DERIVATES, THEIR PROCESS AND PHARMACEUTICAL COMPOSITIONS | IBI ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZIN (IT) | 1988-12-29 | — | — | WO | disclosed |