Phenol

Phenol

SCHEMBL9623399

Oc1cc(Cl)cc(Cl)c1.Oc1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.58
CA2 P00918 2/20 0.58
CA9 Q16790 2/20 0.58
CA14 Q9ULX7 2/20 0.58
CA1 P00915 1/20 0.58
GLA P06280 1/20 0.58
CA3 P07451 1/20 0.58
CA4 P22748 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
TSHR P16473 5/20 0.56
HCAR1 Q9BXC0 1/20 0.48
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MMP3 P08254 1/20 0.42
BCL2L1 Q07817 1/20 0.42
CNR1 P21554 3/20 0.41
CNR2 P34972 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,3,5-Trichlorobenzene SCHEMBL27328470 0.95 CA12 (0.65) CA12CA2CA9CA14CA1
Phenol SCHEMBL28066784 0.84 TSHR (0.71) CA12CA2CA9CA14CA1
Phenol SCHEMBL28216730 0.83 CYP3A4 (0.59) CA12CA2CA9CA14CA1
SCHEMBL330662 0.83
Phenol SCHEMBL28085212 0.82 TSHR (0.68) CA12CA2CA9CA14CA1
Phenol SCHEMBL5544839 0.82 TSHR (0.85) CA12CA2CA9CA14CA1
Chlorobenzene SCHEMBL4890118 0.80 TSHR (0.69) CA12CA2CA9CA14CA1
1,4-Dichlorobenzene SCHEMBL4557393 0.80 CA12 (0.69) CA12CA2CA9CA14CA1
Phenol SCHEMBL11874937 0.80 TSHR (0.67) CA12CA2CA9CA14CA1
Water SCHEMBL16553164 0.80 TSHR (0.57) TSHRHCAR1MAPTCYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed