Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PNLIP | P16233 | 2/20 | 0.38 |
| ▸ | UGT2B7 | P16662 | 5/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623433 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL10824148 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9549996 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL25669585 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9550004 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL8731628 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL18089046 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL15220009 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL541382 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL13206597 | 0.85 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4677233-A | Process for the preparation of (±)-3a-6,6,9a-tetramethylperhydronaphto[2,]furan | FIRMENICH SA (CH) | 1987-06-30 | — | — | US | claimed |
| EP-0170955-A2 | Process for the preparation of (+/-)-3a-6,6,9a-tetramethylperhydronaphto[2,1-b]furan | FIRMENICH SA (CH) | 1986-02-12 | — | — | EP | claimed |
| EP-0170955-B1 | Process for the preparation of (+/-)-3a-6,6,9a-tetramethylperhydronaphto[2,1-b]furan | FIRMENICH SA (CH) | 1992-01-08 | — | — | EP | disclosed |
| US-4677233-A | Process for the preparation of (±)-3a-6,6,9a-tetramethylperhydronaphto[2,]furan | FIRMENICH SA (CH) | 1987-06-30 | — | — | US | disclosed |
| US-4633011-A | INTERMEDIATES FOR THE 1-(2-HYDROXYETHYL)-2,5,5,8, INTERMEDIATES FOR THE 1-(2-HYDROXYETHYL)-2,5,5,8, -TETRAMETHYLPERHYDRONAPHTHALEN-2-OL STARTING MATERIAL | FIRMENICH SA (CH) | 1986-12-30 | — | — | US | disclosed |
| US-4613710-A | CYCLIZATION OF 1B-(2-HYDROXYETHYL)-PERHYDRO-2,5,5,82B-TETRAMETHYL-2B-TRANS-NAPHTHALENOL | FIRMENICH SA (CH) | 1986-09-23 | — | — | US | disclosed |
| EP-0170955-A2 | Process for the preparation of (+/-)-3a-6,6,9a-tetramethylperhydronaphto[2,1-b]furan | FIRMENICH SA (CH) | 1986-02-12 | — | — | EP | disclosed |