SCHEMBL9623596

SCHEMBL9623596

Oc1ccc(Oc2ccc(O)cc2Cl)c(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 7/20 0.57
NR1I2 O75469 1/20 0.57
LMNA P02545 1/20 0.57
PGR P06401 1/20 0.57
HSP90AA1 P07900 1/20 0.57
ADORA3 P0DMS8 1/20 0.57
MAPT P10636 1/20 0.57
HSPA5 P11021 1/20 0.57
HPGD P15428 1/20 0.57
CBR1 P16152 1/20 0.57
TBXA2R P21731 1/20 0.57
SLC6A2 P23975 1/20 0.57
AGTR1 P30556 1/20 0.57
SLC6A3 Q01959 1/20 0.57
HSD17B10 Q99714 1/20 0.56
ESR1 P03372 4/20 0.45
CAMK2A Q9UQM7 1/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27661494 0.91 TTR (0.71) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL9623553 0.87 MEN1 (0.52) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL9622968 0.87 HSD17B10 (0.48) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL10539354 0.86 TTR (0.82) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL29084824 0.83 TTR (0.52) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL10702237 0.83 LTA4H (0.52) TTRCAMK2A
SCHEMBL6913382 0.83 HSD17B10 (0.54) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL28246273 0.83 HSD17B10 (0.54) TTRNR1I2LMNAPGRHSP90AA1
SCHEMBL3781723 0.82 TTR (0.65) TTRNR1I2LMNAPGRHSP90AA1
Ethane SCHEMBL10708644 0.81 HSD17B10 (0.52) TTRNR1I2LMNAPGRHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116144029-A Organosilicon leveling agent, preparation method thereof, black matrix photosensitive resin composition, color filter and liquid crystal display device 阜阳欣奕华材料科技有限公司 2023-05-23 CN disclosed
CN-1230559-A Polyphenols as polycarbonate branching agents GEN ELECTRIC (US) 1999-10-06 CN disclosed
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed