Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.42 |
| ▸ | APEX1 | P27695 | 4/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623627 | 1.00 | TDP1 (0.42) | TDP1APEX1APAF1PLCG1LMNA | |
| SCHEMBL9623972 | 0.96 | TDP1 (0.46) | TDP1APEX1APAF1PLCG1LMNA | |
| SCHEMBL9623971 | 0.96 | TDP1 (0.46) | TDP1APEX1APAF1PLCG1LMNA | |
| SCHEMBL9623995 | 0.93 | TDP1 (0.47) | TDP1APEX1PLCG1LMNAL3MBTL1 | |
| SCHEMBL9623998 | 0.93 | TDP1 (0.47) | TDP1APEX1PLCG1LMNAL3MBTL1 | |
| SCHEMBL9876881 | 0.91 | TDP1 (0.43) | TDP1APEX1APAF1PLCG1LMNA | |
| SCHEMBL9876883 | 0.91 | TDP1 (0.43) | TDP1APEX1APAF1PLCG1LMNA | |
| SCHEMBL9623944 | 0.85 | TDP1 (0.50) | TDP1APEX1PLCG1LMNAL3MBTL1 | |
| SCHEMBL9623946 | 0.85 | TDP1 (0.50) | TDP1APEX1PLCG1LMNAL3MBTL1 | |
| SCHEMBL9877502 | 0.84 | PTGS1 (0.45) | TDP1APEX1PLCG1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145906-B1 | CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-4622318-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-11 | — | — | US | disclosed |
| EP-0145906-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-26 | — | — | EP | disclosed |