Ethylene Glycol

Ethylene Glycol

SCHEMBL9623667

O=C(O)CCCCCCC1(C(=O)O)CCCC1.OCCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.47
CYP4A11 Q02928 3/20 0.47
GPR84 Q9NQS5 5/20 0.47
FFAR1 O14842 2/20 0.47
FFAR4 Q5NUL3 2/20 0.47
CYP2C19 P33261 1/20 0.46
TBXAS1 P24557 2/20 0.44
TSHR P16473 5/20 0.43
LMNA P02545 2/20 0.43
NFKB1 P19838 1/20 0.43
PMP22 Q01453 1/20 0.43
CAMK2A Q9UQM7 1/20 0.40
PPARG P37231 6/20 0.36
PPARD Q03181 6/20 0.36
PPARA Q07869 6/20 0.36
HDAC11 Q96DB2 5/20 0.36
ALDH1A1 P00352 2/20 0.36
TLR2 O60603 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
FABP4 P15090 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251210 0.94 CYP2C19 (0.50) CYP4F2CYP4A11GPR84FFAR1FFAR4
Adipic Acid SCHEMBL4555700 0.94 CYP2C19 (0.50) CYP4F2CYP4A11GPR84FFAR1FFAR4
SCHEMBL278372 0.94 CYP2C19 (0.50) CYP4F2CYP4A11GPR84FFAR1FFAR4
SCHEMBL249976 0.94 CYP2C19 (0.50) CYP4F2CYP4A11GPR84FFAR1FFAR4
Adipic Acid SCHEMBL2227837 0.94 CYP2C19 (0.50) CYP4F2CYP4A11GPR84FFAR1FFAR4
SCHEMBL9437316 0.94 CYP2C19 (0.50) CYP4F2CYP4A11GPR84FFAR1FFAR4
SCHEMBL278034 0.93 CYP2C19 (0.53) CYP4F2CYP4A11GPR84FFAR1FFAR4
SCHEMBL251372 0.93 CYP2C19 (0.53) CYP4F2CYP4A11GPR84FFAR1FFAR4
SCHEMBL7153147 0.93 CYP2C19 (0.53) CYP4F2CYP4A11GPR84FFAR1FFAR4
SCHEMBL278033 0.93 CYP2C19 (0.53) CYP4F2CYP4A11GPR84FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195377-B1 BLENDS OF POLYESTERAMIDES AND POLYAMIDES THE DOW CHEMICAL COMPANY (US) 1992-05-06 EP claimed
EP-0271914-B1 POLYESTERAMIDE WITH IMPROVED COMPRESSION SET THE DOW CHEMICAL COMPANY (US) 1992-01-08 EP disclosed
US-4772649-A Polyesteramide and sufficient carbodiimide to impart improved compression set THE DOW CHEMICAL COMPANY (US) 1988-09-20 US disclosed
EP-0271914-A2 Polyesteramide with improved compression set THE DOW CHEMICAL COMPANY (US) 1988-06-22 EP disclosed