Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL44181 | 1.00 | TDP1 (0.59) | — | |
| Propylene Glycol SCHEMBL7262024 | 1.00 | TDP1 (0.59) | — | |
| Propylene Glycol SCHEMBL259009 | 1.00 | TDP1 (0.59) | — | |
| Propylene Glycol SCHEMBL28430579 | 0.90 | TDP1 (0.48) | — | |
| Propylene Glycol SCHEMBL28215841 | 0.88 | TDP1 (0.59) | — | |
| Propylene Glycol SCHEMBL28304623 | 0.88 | TDP1 (0.59) | — | |
| Propylene Glycol SCHEMBL27821323 | 0.88 | TDP1 (0.59) | — | |
| Propylene Glycol SCHEMBL28216317 | 0.88 | TDP1 (0.59) | — | |
| Propylene Glycol SCHEMBL28260299 | 0.86 | — | — | |
| Isobutanol SCHEMBL28775690 | 0.82 | TSHR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120036424-A | Storage-stable mixtures, method for improving the retention of compounds, rice hulls and/or the use of rice hulls for enhancing the retention of compounds | 帝斯曼知识产权资产管理有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-117202898-A | Novel use | 帝斯曼知识产权资产管理有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117120044-A | Use of propylene glycol mononitrate and limonene for reducing the formation of methane produced and for improving digestibility | 帝斯曼知识产权资产管理有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-117119897-A | Use of gossypol and methane inhibitors for reducing the formation of methane resulting from digestive activities of ruminants | 帝斯曼知识产权资产管理有限公司 | 2023-11-24 | — | — | CN | claimed |
| US-20230355500-A1 | TOPICAL COMPOSITION | LILIGER LTD (IL) | 2023-11-09 | — | — | US | claimed |
| CN-112300004-A | Retinoid derivative based on NO donor, and preparation method and application thereof | 成都大学 | 2021-02-02 | — | — | CN | claimed |
| CN-111712135-A | Storage-stable mixtures | 帝斯曼知识产权资产管理有限公司 | 2020-09-25 | — | — | CN | claimed |
| CN-111491624-A | Storage-stable mixtures | 帝斯曼知识产权资产管理有限公司 | 2020-08-04 | — | — | CN | claimed |
| CN-111491517-A | Storage stable mixture, method for improving compound retention and use of rice hulls and/or rice bran for enhancing compound retention | 帝斯曼知识产权资产管理有限公司 | 2020-08-04 | — | — | CN | claimed |
| CN-111479562-A | Storage-stable mixtures | 帝斯曼知识产权资产管理有限公司 | 2020-07-31 | — | — | CN | claimed |
| EP-0719145-A4 | NITRIC OXIDE DONOR COMPOSITION AND METHOD FOR TREATMENT OF ANAL DISORDERS | CELLEGY PHARMA INC (US) | 1999-01-20 | — | — | EP | claimed |
| US-5693676-A | USING NITROGLYCERIN TO TREAT ANAL FISSURES OR ULCERS, HEMORRHOIDS, LEVATOR SPASMS | NEPTUNE PHARMACEUTICAL CORPORATION (US) | 1997-12-02 | — | — | US | claimed |
| EP-0719145-A1 | NITRIC OXIDE DONOR COMPOSITION AND METHOD FOR TREATMENT OF ANAL DISORDERS | NEPTUNE PHARMACEUTICAL CORPORATION (US) | 1996-07-03 | — | — | EP | claimed |
| US-5504117-A | Pharmacologic preparation for the treatment of anal disorders | NEPTUNE PHARMACEUTICAL CORPORATION (US) | 1996-04-02 | — | — | US | claimed |
| WO-1995032715-A1 | NITRIC OXIDE DONOR COMPOSITION AND METHOD FOR TREATMENT OF ANAL DISORDERS | NEPTUNE PHARMACEUTICAL CORPORATION (US) | 1995-12-07 | — | — | WO | claimed |
| EP-0325534-B1 | PROCESS FOR THE SYNTHESIS OF GLYCERYL MONO NITRATES BY BIOCONVERSION OF NITROGLYCEROL | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1991-05-02 | — | — | EP | claimed |
| US-4985357-A | YEASTS, FUNGI, PROTOZOA | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1991-01-15 | — | — | US | claimed |
| US-4718953-A | High explosive compound in nitrate salt matrix | C-I-L INC. (CA) | 1988-01-12 | — | — | US | claimed |
| US-4094714-A | CARBAMIC ACID DERIVATIVE | ICI AUSTRALIA LIMITED (AU) | 1978-06-13 | — | — | US | claimed |
| US-4050970-A | CARBAMIC ACID DERIVATIVE | ICI AUSTRALIA LIMITED (AU) | 1977-09-27 | — | — | US | claimed |