Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 8/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872496 | 0.84 | PTGER2 (0.45) | PTGER2PTGER4PTGER3TSHRHTT | |
| SCHEMBL28670909 | 0.83 | PTGER2 (0.44) | PTGER2PTGER4PTGER3TSHRHTT | |
| SCHEMBL11417780 | 0.81 | PTGER2 (0.43) | PTGER2PTGER4PTGER3TSHRHTT | |
| SCHEMBL9808404 | 0.80 | PTGER2 (0.42) | PTGER2PTGER4PTGER3TSHRHTT | |
| SCHEMBL9015808 | 0.79 | PTGER2 (0.45) | PTGER2PTGER4PTGER3TSHRHTT | |
| SCHEMBL11690713 | 0.79 | PTGER2 (0.64) | PTGER2PTGER4PTGER3TSHRMEN1 | |
| SCHEMBL11690701 | 0.79 | PTGER2 (0.64) | PTGER2PTGER4PTGER3TSHRMEN1 | |
| SCHEMBL11690709 | 0.79 | PTGER2 (0.64) | PTGER2PTGER4PTGER3TSHRMEN1 | |
| SCHEMBL22125277 | 0.78 | PTGER2 (0.43) | PTGER2PTGER4PTGER3TSHRHTT | |
| SCHEMBL16719044 | 0.76 | PTGER2 (0.40) | PTGER2PTGER4PTGER3TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319576-B1 | PROSTAGLANDIN DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) | 1992-01-08 | — | — | EP | disclosed |
| EP-0319576-A1 | PROSTAGLANDIN DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES. | ISTITUTO BIOCHIMICO ITALIANO (IT) | 1989-06-14 | — | — | EP | disclosed |
| WO-1988010252-A1 | PROSTAGLANDIN DERIVATES, THEIR PROCESS AND PHARMACEUTICAL COMPOSITIONS | IBI ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZIN (IT) | 1988-12-29 | — | — | WO | disclosed |