Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 7/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623743 | 0.80 | PTGER2 (0.49) | PTGER2PTGER4PTGER3ZDHHC7TSHR | |
| SCHEMBL30801437 | 0.76 | ZDHHC7 (0.54) | ZDHHC7TSHRLMNAABCB1 | |
| SCHEMBL11119362 | 0.76 | PTGER2 (0.39) | PTGER2PTGER4PTGER3TSHRMEN1 | |
| SCHEMBL11251902 | 0.75 | PTGER2 (0.52) | PTGER2PTGER4PTGER3TSHRALDH1A1 | |
| SCHEMBL9644387 | 0.75 | ZDHHC7 (0.51) | ZDHHC7TSHRLMNAABCB1 | |
| SCHEMBL5194966 | 0.71 | THRB (0.48) | PTGER2PTGER4PTGER3ZDHHC7TSHR | |
| SCHEMBL28636423 | 0.71 | THRB (0.48) | PTGER2PTGER4PTGER3ZDHHC7TSHR | |
| SCHEMBL11244320 | 0.71 | TLR4 (0.35) | PTGER2PTGER4PTGER3HTT | |
| SCHEMBL38665252 | 0.71 | ZDHHC7 (0.51) | ZDHHC7TSHRLMNAABCB1 | |
| SCHEMBL11861322 | 0.70 | PTGER2 (0.35) | PTGER2PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425584-A1 | PROSTAGLANDIN-DERIVATIVES HAVING ANTITHROMBOTIC ACTIVITY | IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) | 1991-05-08 | — | — | EP | disclosed |
| WO-1990003170-A2 | PROSTAGLANDIN-DERIVATIVES HAVING ANTITHROMBOTIC ACTIVITY | IBI ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.P.A. (IT) | 1990-04-05 | — | — | WO | disclosed |