Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.36 |
| ▸ | SHBG | P04278 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624018 | 0.91 | POLB (0.52) | POLBMAPTCYP17A1SHBGSMN1; SMN2 | |
| SCHEMBL9623549 | 0.91 | POLB (0.52) | POLBMAPTCYP17A1SHBGSMN1; SMN2 | |
| SCHEMBL3750366 | 0.80 | POLB (0.62) | POLBMAPTCYP17A1SHBGSMN1; SMN2 | |
| SCHEMBL9624222 | 0.78 | POLB (0.35) | POLBMAPT | |
| SCHEMBL9160890 | 0.78 | POLB (0.60) | POLBMAPTCYP17A1SHBGSMN1; SMN2 | |
| SCHEMBL9623709 | 0.77 | ESR1 (0.37) | CYP19A1 | |
| SCHEMBL3753955 | 0.76 | POLB (0.55) | POLBMAPTCYP17A1SHBGSMN1; SMN2 | |
| SCHEMBL12992189 | 0.75 | POLB (0.67) | POLBMAPTCYP17A1SHBGSMN1; SMN2 | |
| SCHEMBL2789952 | 0.75 | POLB (0.67) | POLBMAPTCYP17A1SHBGSMN1; SMN2 | |
| SCHEMBL15963152 | 0.75 | POLB (0.67) | POLBMAPTCYP17A1SHBGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |