Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624194 | 1.00 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL3332557 | 0.78 | GRM5 (0.33) | — | |
| SCHEMBL3332564 | 0.78 | GRM5 (0.33) | — | |
| SCHEMBL9624613 | 0.73 | CYP11B2 (0.58) | NPC1RAB9AKMT2AMEN1GRM4 | |
| SCHEMBL9624615 | 0.73 | CYP11B2 (0.58) | NPC1RAB9AKMT2AMEN1GRM4 | |
| SCHEMBL19538990 | 0.72 | NPC1 (0.62) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL229328 | 0.72 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL229329 | 0.72 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL9394256 | 0.72 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL31560044 | 0.72 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145906-B1 | CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-4985555-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4871730-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| EP-0268307-A2 | New starting compounds for cephem compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-25 | — | — | EP | disclosed |
| US-4622318-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-11 | — | — | US | disclosed |
| EP-0145906-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-26 | — | — | EP | disclosed |
| EP-0133678-A2 | New cephem compounds, processes for preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-06 | — | — | EP | disclosed |