Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831100 | 0.92 | GSK3B (0.46) | MAPTKMT2ANPC1RAB9APSMD14 | |
| SCHEMBL13725780 | 0.92 | GSK3B (0.46) | MAPTKMT2ANPC1RAB9APSMD14 | |
| SCHEMBL25485940 | 0.89 | KMT2A (0.65) | MAPTKMT2ANPC1RAB9APSMD14 | |
| SCHEMBL9176989 | 0.87 | GSK3B (0.63) | MAPTKMT2ANPC1RAB9APSMD14 | |
| SCHEMBL9176995 | 0.87 | GSK3B (0.63) | MAPTKMT2ANPC1RAB9APSMD14 | |
| SCHEMBL8988877 | 0.86 | MAPT (0.52) | MAPTKMT2ANPC1RAB9APSMD14 | |
| SCHEMBL12513087 | 0.85 | NPC1 (0.50) | MAPTKMT2ANPC1RAB9APSMD14 | |
| SCHEMBL12513624 | 0.84 | RAB9A (0.52) | MAPTKMT2ANPC1RAB9APSMD14 | |
| SCHEMBL4638072 | 0.83 | KMT2A (0.59) | MAPTKMT2ANPC1RAB9APSMD14 | |
| SCHEMBL4637916 | 0.83 | KMT2A (0.59) | MAPTKMT2ANPC1RAB9APSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305115-B1 | IMPROVEMENTS IN OR RELATING TO RADIATION SENSITIVE COMPOUNDS | E.I. du Pont de Nemours and Company (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4933452-A | Radiation sensitive isocyanurate compounds | AGFA-GEVAERT. N.V. (BE) | 1990-06-12 | — | — | US | disclosed |