Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647774 | 0.85 | CACNA1F (0.48) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL9624979 | 0.85 | ADRB3 (0.61) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL9624818 | 0.85 | ADRB3 (0.61) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL9624435 | 0.81 | HDAC3 (0.52) | MAPTLMNAALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL10645824 | 0.80 | ADRB3 (0.64) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL9624733 | 0.76 | ADRB3 (0.60) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL9624596 | 0.76 | CACNA1F (0.60) | MAPTCACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL9226340 | 0.75 | CACNA1F (0.61) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL7574166 | 0.75 | CACNA1F (0.61) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL9625593 | 0.75 | CACNA1F (0.61) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155268-A | Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides | THE UPJOHN COMPANY (US) | 1992-10-13 | — | — | US | disclosed |