SCHEMBL9624735

SCHEMBL9624735

COc1ccc(P(c2ccncc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
KDM4E B2RXH2 3/20 0.53
NPC1 O15118 3/20 0.53
CYP2C9 P11712 2/20 0.53
CYP2C19 P33261 2/20 0.53
RAB9A P51151 2/20 0.53
CYP2D6 P10635 2/20 0.53
CYP3A4 P08684 1/20 0.53
HPGD P15428 1/20 0.53
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
LMNA P02545 2/20 0.47
USP2 O75604 1/20 0.46
NFE2L2 Q16236 1/20 0.45
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5427189 0.86 CA1 (0.58) KDM4ENPC1RAB9ACYP3A4CA12
Hydrochloric Acid SCHEMBL10921791 0.86 CA1 (0.58) KDM4ENPC1RAB9ACYP3A4CA12
Hydrochloric Acid SCHEMBL21724600 0.86 CA1 (0.58) KDM4ENPC1RAB9ACYP3A4CA12
Hydrochloric Acid SCHEMBL11039728 0.86 CA1 (0.58) KDM4ENPC1RAB9ACYP3A4CA12
SCHEMBL50047 0.86 CA1 (0.65) KDM4ENPC1RAB9ACYP3A4CA12
SCHEMBL15658842 0.86 CA1 (0.65) KDM4ENPC1RAB9ACYP3A4CA12
SCHEMBL5713323 0.84 CA1 (0.61) KDM4ENPC1RAB9ACYP3A4CA12
SCHEMBL31378153 0.84 CA1 (0.61) KDM4ENPC1RAB9ACYP3A4CA12
SCHEMBL31328597 0.84 CA1 (0.61) KDM4ENPC1RAB9ACYP3A4CA12
Iodide SCHEMBL29883618 0.84 CA1 (0.61) KDM4ENPC1RAB9ACYP3A4CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0307026-B1 PROCESS FOR THE PREPARATION OF A BUTENE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-03-18 EP disclosed
EP-0271144-B1 PROCESS FOR THE CARBONYLATION OF ACETYLENICALLY UNSATURATED COMPOUNDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-10-16 EP disclosed
EP-0282142-B1 PROCESS FOR THE CARBONYLATION OF OLEFINICALLY UNSATURATED COMPOUNDS WITH A PALLADIUM CATALYST SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-09-11 EP disclosed
US-4940787-A Process for the carbonylation of acetylenic unsaturated compounds SHELL OIL COMPANY (US) 1990-07-10 US disclosed
EP-0307026-A1 Process for the preparation of a butene SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-03-15 EP disclosed
US-4786443-A Process for the carbonylation of olefinically unsaturated compounds with a palladium catalyst SHELL OIL COMPANY (US) 1988-11-22 US disclosed
EP-0282142-A1 Process for the carbonylation of olefinically unsaturated compounds with a palladium catalyst SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-09-14 EP disclosed
EP-0271144-A2 Process for the carbonylation of acetylenically unsaturated compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-06-15 EP disclosed