Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.55 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532863 | 0.95 | HPGD (0.58) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL9080508 | 0.88 | CACNA1F (0.62) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL10878888 | 0.86 | KCNH2 (0.54) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL9624530 | 0.83 | KDM4E (0.58) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL6460284 | 0.82 | KCNH2 (0.47) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL9628026 | 0.81 | KCNH2 (0.76) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL10528894 | 0.81 | KCNH2 (0.57) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL16976564 | 0.80 | KDM4E (0.65) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL8763605 | 0.80 | KDM4E (0.59) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL9624804 | 0.80 | KCNH2 (0.66) | HPGDKDM4EALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155268-A | Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides | THE UPJOHN COMPANY (US) | 1992-10-13 | — | — | US | disclosed |