Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050588 | 0.90 | ALDH1A1 (0.50) | ALDH1A1HDAC1HDAC2HDAC7HDAC8 | |
| SCHEMBL9625495 | 0.87 | HDAC1 (0.60) | ALDH1A1HDAC1HDAC2HDAC7HDAC8 | |
| SCHEMBL19899249 | 0.87 | ALDH1A1 (0.46) | ALDH1A1HDAC1HDAC2HDAC7HDAC8 | |
| SCHEMBL4726173 | 0.83 | HDAC1 (0.52) | ALDH1A1HDAC1HDAC2HDAC7HDAC8 | |
| SCHEMBL11166849 | 0.81 | HDAC1 (0.55) | ALDH1A1HDAC1HDAC2HDAC7HDAC8 | |
| SCHEMBL2448748 | 0.81 | HDAC1 (0.58) | ALDH1A1HDAC1HDAC2HDAC7HDAC8 | |
| SCHEMBL18050485 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HDAC1HDAC2HDAC7HDAC8 | |
| SCHEMBL19598979 | 0.80 | ALDH1A1 (0.81) | ALDH1A1SOAT1TSHRNPSR1LMNA | |
| SCHEMBL1718009 | 0.80 | ALDH1A1 (0.81) | ALDH1A1SOAT1TSHRNPSR1LMNA | |
| SCHEMBL18050542 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CA1CA2SOAT1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250997-B1 | VALPROIC AND (E)-2-VALPROENOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREFROM | CHIESI FARMACEUTICI S.p.A. (IT) | 1992-04-15 | — | — | EP | claimed |