SCHEMBL9625019

SCHEMBL9625019

O=C(c1ccccc1)c1ccc2ccc3ccccc3c2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
ATM Q13315 1/20 0.57
ALDH1A1 P00352 6/20 0.54
MAPT P10636 1/20 0.53
HPGD P15428 1/20 0.53
SRD5A2 P31213 1/20 0.52
CASP3 P42574 1/20 0.51
GFER P55789 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
HIF1A Q16665 2/20 0.50
HSD17B10 Q99714 2/20 0.50
CYP1B1 Q16678 1/20 0.50
GRIN2D O15399 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14124776 0.93 SRD5A2 (0.59) NPC1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL28211179 0.91 ALDH1A1 (0.66) NPC1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL9624651 0.87 ALDH1A1 (0.49) NPC1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL2469905 0.84 GRIN2D (0.66) MEN1KMT2AL3MBTL1TDP1ALDH1A1
SCHEMBL11818284 0.84 ALDH1A1 (0.72) NPC1RAB9AMEN1KMT2ATDP1
SCHEMBL9624294 0.83 ALDH1A1 (0.55) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL9624756 0.82 CDC25B (0.64) ATMALDH1A1HSD17B10
SCHEMBL30776760 0.82 ATM (0.64) NPC1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL29834246 0.82 MEN1 (0.75) NPC1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL30776759 0.82 ATM (0.64) NPC1RAB9AMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325825-B1 PHOSPHORESCENT MATERIALS THE POST OFFICE (GB) 1992-09-16 EP disclosed
US-5100580-A Polycyclic aromatic ketones, printing ink and paper coating, activator in amino resin matrix THE POST OFFICE (GB) 1992-03-31 US disclosed
EP-0325825-A1 Phosphorescent materials THE POST OFFICE (GB) 1989-08-02 EP disclosed