Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724792 | 0.81 | MAPT (0.51) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL9624785 | 0.79 | NPSR1 (0.38) | PPARGPPARAMAPTKMT2AHPGD | |
| SCHEMBL9581015 | 0.79 | BCL9 (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL6836201 | 0.76 | KMT2A (0.56) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL27837371 | 0.74 | ALDH1A1 (0.43) | HDAC1HDAC2MAPTELANEKMT2A | |
| SCHEMBL28125267 | 0.74 | KMT2A (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL28125291 | 0.74 | KMT2A (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL9395594 | 0.74 | KMT2A (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL28125274 | 0.74 | KMT2A (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4205796 | 0.73 | KDM4E (0.55) | MAPTKMT2AHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301511-B1 | OPTICALLY ACTIVE COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | CANON KABUSHIKI KAISHA (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-5073306-A | Trifluoromethylalkyl substituted | CANON KABUSHIKI KAISHA (JP) | 1991-12-17 | — | — | US | disclosed |
| US-4918213-A | HAVING A TRIFLUOROMETHYL GROUP ATTACHED TO ASYMMETRIC CARBON ATOM; STABLE; OPTICAL DEVICES | CANON KABUSHIKI KAISHA (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0301511-A1 | Optically active compound and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1989-02-01 | — | — | EP | disclosed |