Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624390 | 0.93 | RARB (0.54) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9623890 | 0.89 | RARB (0.54) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9624891 | 0.89 | RARB (0.54) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9097155 | 0.85 | RARB (0.46) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9238185 | 0.85 | RARB (0.62) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9240113 | 0.85 | RARB (0.62) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9239700 | 0.85 | RARB (0.62) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9236089 | 0.85 | RARB (0.62) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9624985 | 0.84 | RARB (0.48) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9624607 | 0.84 | RARB (0.48) | RARBRAB9ANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255219-B1 | OMEGA-SUBSTITUTED, OPTICALLY ACTIVE 2-ALKANOL ESTER DERIVATIVES | Chisso Corporation (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-5047172-A | W-substituted, optically active alkanol ester derivatives | CHISSO CORPORATION (JP) | 1991-09-10 | — | — | US | disclosed |