Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389754 | 1.00 | CHRM2 (0.40) | CHRM2CHRM5CHRM1 | |
| SCHEMBL9009633 | 0.78 | CHRM2 (0.64) | CHRM2CHRM5CHRM1 | |
| SCHEMBL9009653 | 0.78 | CHRM2 (0.64) | CHRM2CHRM5CHRM1 | |
| SCHEMBL9009632 | 0.78 | CHRM2 (0.64) | CHRM2CHRM5CHRM1 | |
| SCHEMBL9009655 | 0.74 | CHRM2 (0.39) | CHRM2CHRM5CHRM1 | |
| SCHEMBL9497662 | 0.74 | CHRM2 (0.39) | CHRM2CHRM5CHRM1 | |
| SCHEMBL10389008 | 0.74 | CHRM2 (0.46) | CHRM2CHRM5CHRM1 | |
| SCHEMBL10389007 | 0.74 | CHRM2 (0.46) | CHRM2CHRM5CHRM1 | |
| SCHEMBL10390526 | 0.71 | CHRM2 (0.40) | CHRM2CHRM5CHRM1 | |
| SCHEMBL9456827 | 0.70 | CHRM2 (0.42) | CHRM2CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308284-B1 | 1,2,5,6-TETRAHYDROPYRIDINE OXIME DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1992-03-11 | — | — | EP | disclosed |
| US-4902699-A | Oxime of 1, 2, 5, 6-tetrahydropyridine compounds their use as medicaments and the compositions containing them | ROUSSEL UCLAF (FR) | 1990-02-20 | — | — | US | disclosed |
| EP-0308284-A1 | 1,2,5,6-Tetrahydropyridine oxime derivatives, process for their preparation, their use as pharmaceutical compounds and compositions containing them | ROUSSEL-UCLAF (FR) | 1989-03-22 | — | — | EP | disclosed |