SCHEMBL9625656

SCHEMBL9625656

O=C(c1ccc(/N=N/c2ccc(O)cc2)cc1)c1ccc2ccccc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.67
KMT2A Q03164 5/20 0.67
NPC1 O15118 3/20 0.67
RAB9A P51151 3/20 0.67
HSP90AA1 P07900 2/20 0.67
CLK1 P49759 1/20 0.58
DYRK1A Q13627 1/20 0.58
DYRK1B Q9Y463 1/20 0.58
HSD17B14 Q9BPX1 1/20 0.54
ESR1 P03372 3/20 0.53
ESR2 Q92731 3/20 0.53
DEGS1 O15121 1/20 0.53
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
LMNA P02545 4/20 0.48
MAPT P10636 4/20 0.48
HTT P42858 3/20 0.48
PKM P14618 1/20 0.48
HPGD P15428 1/20 0.48
ACHE P22303 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9625658 1.00 MEN1 (0.67) MEN1KMT2ANPC1RAB9AHSP90AA1
SCHEMBL5383875 0.90 MEN1 (0.76) MEN1KMT2ANPC1RAB9ACLK1
SCHEMBL9715061 0.82 MEN1 (0.74) MEN1KMT2ANPC1RAB9ACLK1
SCHEMBL8393638 0.81 MEN1 (0.93) MEN1KMT2ANPC1RAB9ACLK1
SCHEMBL9715104 0.80 HTT (0.68) MEN1KMT2ANPC1RAB9ACLK1
SCHEMBL30250451 0.80 CES2 (0.74) MEN1KMT2ANPC1RAB9ACLK1
SCHEMBL29613672 0.80 CES2 (0.74) MEN1KMT2ANPC1RAB9ACLK1
SCHEMBL941698 0.80 CES2 (0.74) MEN1KMT2ANPC1RAB9ACLK1
SCHEMBL29834246 0.79 MEN1 (0.75) MEN1KMT2ANPC1RAB9ACLK1
SCHEMBL124894 0.79 MEN1 (0.75) MEN1KMT2ANPC1RAB9ACLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325825-B1 PHOSPHORESCENT MATERIALS THE POST OFFICE (GB) 1992-09-16 EP disclosed
US-5100580-A Polycyclic aromatic ketones, printing ink and paper coating, activator in amino resin matrix THE POST OFFICE (GB) 1992-03-31 US disclosed
EP-0325825-A1 Phosphorescent materials THE POST OFFICE (GB) 1989-08-02 EP disclosed