Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11773628 | 0.91 | ALDH1A1 (0.55) | ALDH1A1HTTTP53POLBKDM4E | |
| SCHEMBL9153407 | 0.87 | ALDH1A1 (0.51) | ALDH1A1HTTTP53POLBKDM4E | |
| SCHEMBL9624323 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HTTTP53POLBKDM4E | |
| SCHEMBL5958908 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HTTTP53POLBKDM4E | |
| SCHEMBL13957715 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HTTTP53POLBKDM4E | |
| SCHEMBL17446693 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HTTTP53POLBKDM4E | |
| SCHEMBL7502491 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HTTTP53POLBKDM4E | |
| SCHEMBL8446739 | 0.83 | TP53 (0.51) | ALDH1A1HTTTP53POLBKDM4E | |
| SCHEMBL30278697 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HTTTP53POLBKDM4E | |
| SCHEMBL10651329 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HTTTP53POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0265412-B1 | 2-AMINO-4-PHOSPHONYL-BUTANOATE DERIVATES AND PREPARATION OF 2-AMINO-4-PHOSPHINYL BUTANOIC ACIDS | Monsanto Company (US) | 1992-03-11 | — | — | EP | disclosed |
| US-4764620-A | 4-phosphorus-2-phthalimidobutyrate intermediates | MONSANTO COMPANY (US) | 1988-08-16 | — | — | US | disclosed |
| EP-0265412-A2 | 2-Amino-4-Phosphonyl-butanoate derivates and preparation of 2-amino-4-phosphinyl butanoic acids | Monsanto Company (US) | 1988-04-27 | — | — | EP | disclosed |