Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 7/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626386 | 0.93 | KDM4E (0.45) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9626227 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9627822 | 0.89 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9636153 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9627123 | 0.84 | TOP2A (0.39) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9626383 | 0.82 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL10863653 | 0.80 | KDM4E (0.53) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9627087 | 0.80 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL10914440 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9627817 | 0.78 | KDM4E (0.62) | ALDH1A1KDM4EHPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198192-B1 | 7-AMINO-1-(SUBST.CYCLOPROPYL)-1,4 -DIHYDRO-4-OXO-QUINOLINE CARBOXYLIC ACIDS, METHOD FOR THEIR PREPARATION, AND ANTIBACTERIAL AGENTS CONTAINING THEM | BAYER AG (DE) | 1992-05-13 | — | — | EP | claimed |
| EP-0198192-A1 | 7-Amino-1-(subst.cyclopropyl)-1,4 -dihydro-4-oxo-quinoline carboxylic acids, method for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1986-10-22 | — | — | EP | claimed |
| EP-0198192-B1 | 7-AMINO-1-(SUBST.CYCLOPROPYL)-1,4 -DIHYDRO-4-OXO-QUINOLINE CARBOXYLIC ACIDS, METHOD FOR THEIR PREPARATION, AND ANTIBACTERIAL AGENTS CONTAINING THEM | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| EP-0300155-A2 | Cyclopropyl amines | BAYER AG (DE) | 1989-01-25 | — | — | EP | disclosed |
| EP-0198192-A1 | 7-Amino-1-(subst.cyclopropyl)-1,4 -dihydro-4-oxo-quinoline carboxylic acids, method for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1986-10-22 | — | — | EP | disclosed |